A student from Carnegie Mellon University, for his assignment in his intro to Robotics class, programmed a motorized Lego car so it could be controlled by a Wii-mote and Nunchuk.
His assignment was part of a project that was intended as a small-scale demonstration for possible use in Urban Search and Rescue programs.
The student stated; This robot is composed of Legos and uses a handyboard as the control hardware. It has 4 wheel drive each controlled by a lego motor, and a pan tilt mount for directing light and the video camera. The Wii Remote talks to a MacBook Pro over bluetooth to modified DarwiinRemote software, and the computer in turn communicates with the robot over a serial port.
From: Gaming Today