The mutually beneficial agreement covers the two companies' existing patents as well as those filed over the next 10 years.
The agreement marks the third deal that Samsung has announced in the past couple weeks. It also reached deals with Google and Ericsson, both to settle litigation and to prevent future issues.
"Innovation is stifled all too often in today's overly-litigious environment," said Dan Lang, Cisco's Vice President of Intellectual Property. "By cross-licensing our patent portfolios, Cisco and Samsung are taking important steps to reverse the trend and advance innovation and freedom of operation."